Brendan Rodgers will look for his side to put all their efforts into domestic matters after learning their European fate, starting with Hamilton on Wednesday.
Having been drawn against Zenit St Petersburg on Monday, Celtic will only have to focus on the league this side of Christmas as the festive period draws near.
The Hoops lost a two goal lead to Hibernian at the weekend, but extended their lead at the top of the table to five points with a game in hand over second place.
Hamilton haven’t won a game since their trip to Ibrox last month and currently sit ninth in the league table.
Patrick Roberts will be out until 2018 with a hamstring that has plagued him since his return to Glasgow at the end of August.
Anthony Ralston is training again and won’t need surgery on a meniscus problem that has kept him out of action since September.
The Accies have no injury concerns going into the game.